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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

For a few years, Namibia's dollar has been depreciating against many currencies, providing affordable opportunities for travel. The best-priced flights generally avoid South African and European school-holiday times, especially late December and January.
单词unique 联想记忆:

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

Rose McGowan accused producer Harvey Weinstein of rape this time last year, sparking an avalanche of allegations in the entertainment industry and beyond.
'12 Years A Slave' is shattering and anguishing, a singular anomaly in an entertainment medium. More than that, Steve McQueen's hugely ambitious chronicle of slavery in America is revelatory, a work of art that has been embraced by mainstream audiences. That's a testimony to the power of art (as expressed in John Ridley's script and performances by Chiwetel Ejiofor, Lupita Nyong'o and Michael Fassbender, among others), and heartening evidence of moviegoers' hunger for substance and meaning in the films they choose to see.

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

过去三年,由于北京决定在官方总收入中增加新的服务费,有关中国票房增长的结论变得复杂起来。

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

在叙利亚问题上,普京说,俄罗斯将继续开展军事行动,直至政治进程启动。他说,必须让叙利亚人民自己决定由谁来治理这个国家。他还说,他不知道俄罗斯是否需要在叙利亚设立永久军事基地。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

In an emailed statement, FIFA said that during group stage matches, it sold a total of 143,364 of the cheapest tickets, which amounted to roughly 3,000 such tickets available per match.
科学圈外的人士对论文撤稿的反应不一。
添加一些个性元素。把自己家人的照片或东西放在桌子上可以提醒你为什么你要努力工作。
这种旅行枕可以随意弯曲变形,您的头怎么放都行。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

是的,另一个萨克拉门托不该垫底的原因就是:费城今年有权和他们交换选秀权。因此,国王队完全没可能得到状元签,而且他们得到前三签位的可能性也很低。
In the most significant change in methodology since this ranking was first published in 2005, the FT now collects information about alumni’s first jobs after graduation. These data are used in conjunction with information about their current jobs, three years later. This allows the FT to calculate their salary increase since graduation — a new ranking criterion — as well as their career progress (see methodology).
达奇斯说:在这一年中,卡夫支持转基因食物,这个决定使得这个品牌成为了2012年的输家。
这两笔交易中最大的风险在于伊巴卡和塔克这个夏天即将成为自由球员,但是失去一到两名球员的痛苦和早早的在五月就被淘汰出季后赛相比就不算什么了。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

The Globes are unique in celebrating both film and television. Perhaps more than ever before, those lines were blurred Sunday, capping a year in which TV was much celebrated as the more dynamic storytelling medium. The beloved and now concluded 'Breaking Bad' earned some of the night's loudest cheers for its first Globe wins: best drama TV series and best actor in a drama for Bryan Cranston.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

2015年英国《金融时报》全球高管工商管理硕士课程(Global Executive MBA,简称全球EMBA)排行榜由于两个原因而引人注目。不仅因为这是英国《金融时报》发布的第100个商学院排行榜,也是因为今年首次有一个主办方包含一所中国内地商学院的项目拔得头筹。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

每平方英尺单价:667美元(每平方米约合人民币4.6万元)
单词original 联想记忆:

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

2010年英文新年祝福邮件
As foreign minister, Margot Wallstrom, who broke free from a violent relationship in her 20s, is challenging assumptions in a traditionally male sphere.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

deprivation
The Meyerowitz Stories

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

Beyoncé vs. Jennifer
据牛津经济研究院(Oxford Economics)估算,若剔除价格影响,中国10月进口量同比降幅为2.6%。
澳大利亚
It’s the time of the year for list making! This Youku video clip named the nine hottest lines on China’s web this year. The Yangtze Evening Post, an influential newspaper, is the original list compiler.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

几十年来,白人身份认同话语只存在于白人至上论的语境之中。当白人至上论成为禁忌,白人身份政治就陷入一种失语状态。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

Adapted from an online novel Queen of No.11 Agent, the TV series is about the adventure of a female slave Chu Qiao and her romance with a prince Yan Xun.
Brazil

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

他们预测,在未来几十年中,炎热天气会变得更糟,这种天气已经在世界各地导致森林死亡、植物和动物物种灭绝、陆地冰层融化,以及海平面上升速度加快。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

7. 建立声誉。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

这部由塞巴斯蒂安.马拉比(Sebastian Mallaby)所著的《知者:格林斯潘传》(The Man Who Knew),是这项奖金额为3万英镑的奖项的第12位获奖者。该奖项奖励的是年度“最令人瞩目和愉悦的”图书。
Another positive of the scheme is that it encourages professional flexibility, preparing the young for the career zigging and zagging that might be necessary in the modern world of work.
Here are some of the trends that emerge from this year’s BrandZ rankings:
Tesla has an order backlog of $226 million. At the production run rate of 1000 cars a week expected at the end of 2014, that translates to a 30-week backlog.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

adj. 受影响的,受感动的,受疾病侵袭的 adj. 做
Master of None
判断权在你手里。
自该学校的国际管理学硕士(International Master in Management)项目首次被纳入榜单以来,该学校的排名在过去两年上升31个位置。
“I don’t think there are any companies that have survived big assaults from two of the biggest beasts in the hedge fund jungle,” says Ms Simpson of Calpers. “He is cool, calm and collected — the corporate exemplar of ‘Keep calm and carry on’.”

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

3. In Cannes, they speak English
element

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

但是,海外机构投资者表示,随着中国经济增长放慢,香港房地产市场已经过热,正在进入调整阶段。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

INDOORS: The two-story house, of brick and stucco with a ceramic tile roof, was designed by Dorr & Dorr, completed in 1916 and renovated over the last 15 years. The style is part Prairie, part Arts and Crafts, employing clean lines, open space, elegant woodwork and colored glass. Renovations were done by Joseph Metzler of Sala Architects in Minneapolis.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

Anxiety has been fanned by the build-up of corporate debt in emerging markets, which doubled between 2008 and 2014 and has been one of the fastest growing areas of the global bond market.
而如果国王队签位掉出前10的话公牛队又会得到他们的签,所以在不妨碍球队重建的情况下,国王队不仅仅是不能进入季后赛,最好还是在倒数前十的队列中。
或许不会是一个超新星,但是会有好球员快速地把他们拉回正轨,比我们之前讨论的其他队伍都要快。打完这个赛季,还完之前的债,然后就可以潇洒甩头,大步向前了。
加快培育壮大新兴产业。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
From the themed collection: 大批产学研合作项目落户湾区
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

TV Movie: “Sherlock: The Abominable Bride (Masterpiece)” (PBS)
n. 预定,保留意见
n. 反映,映像,折射,沉思,影响
But whether another hit product can emerge to fend off questions about Apple’s life after Jobs, Mr Cook learnt long ago to be patient and trust his instincts, just as he did when he ignored the doubters to join the then-struggling company in 1998.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

The price of U.S. benchmark West Texas Intermediate crude, which is traded on the New York Mercantile Exchange, has been kept lower by problems transporting the oil to markets. Those troubles have eased recently, but Sabine Schels, head of fundamental commodity research at Bank of America Merrill Lynch, doubts the problems will disappear.
Plenty of dark clouds loom over the U.S. job market -- particularly the potential double-punch of tax increases and spending cuts known as the fiscal cliff.[qh]

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Due to the rapid growth of the online gaming sector, NetEase founder Ding Lei doubled his wealth to 96 billion yuan, surpassing Baidu Inc Chairman Robin Li and ranking third in the IT rich list.
报告指出,缺少资金和经验是大学生创业者们面临的最大障碍,40%的年轻创业者们依赖于诸如来自银行、投资机构、学校和政府等机构贷款的外部资金。
报告指出,2016年中国网民数量增加了4299万人,同比去年增长6.2个百分点,而网民总人数占到了中国总人口的53.2%。
交通运输部科学研究院近日发布的报告显示,北京位居全国十大最拥堵城市排行榜第三,排在济南、哈尔滨之后。
China's manufacturing sector last month expanded at the slowest pace since March.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

In a bid to raise awareness of one of the world's most endangered species and the Chengdu Panda Base in China, the 108 performers were hard to miss as they entertained Londoners and children during school visits with conservationist and base ambassador Nigel Marven.
5、Poor e-mail communication
台风艾玛

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

Hope you enjoy the happiness of New Year and all the trimmings.祝你享尽新年佳节的快乐和新年的礼品。
4. 欧佩克的下一步行动。说到去年的油价暴跌,石油输出国组织(OPEC)起了很大作用(或者说要承担很大责任)。虽然许多评论人士都说欧佩克保持原油产量不变无关紧要,然而,仅油价在该组织11月份会议过后出现暴跌这一事实便充分证明了该组织对油价走势的影响力。目前,欧佩克——更确切地说是沙特——仍在坚持己见,毫无下调生产配额的迹象。2015年这一情况是否会得以延续,仍有待观察。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: 三大因素导致水泥行业产能过剩
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

PRICE PER SQUARE FOOT: $667
这一新数据公布之际,杜特尔特正抵御国内外对其禁毒运动的指责,已有60万名潜在嫌疑人向当局自首。
Confidence and a good elevator speech can take any pitch to the next level. The first marketing any company experiences comes from its founder. Spend time learning how to share your vision without coming across as “salesy.” Don’t be afraid to ask for the sale, but remember: the client is always the focus.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

我们的前路应有尽有,我们的前路一无所有……
Shipments to China cratered by 14.4 per cent year-on-year to Rmb737.5bn in January. That’s from a 4 per cent drop in December, and versus expectations for a 1.8 per cent rise.
单词intended 联想记忆:

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

Gitanjali表示,她想要进一步改善改设备,这样它最终就能进入市场了。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

该数据显示10月份下半月北京、天津、上海、深圳、厦门和郑州新建住宅价格出现了环比下滑。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

7.你们公司的人事在一个求职网站上发现了你的简历。
将第1题到第9题的分数相加,计算自己在“消极情感”维度的得分。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

We'll start our review with the South American nations, and who else could we begin with, but the hosts Brazil. Rewind 18 months and they looked like they'd be struggling, but the appointment of 'Big Phil' Scolari has been inspired, and he's brought a belief to the team that was previously missing. Last years 3:0 demolition of Spain in the Confederations Cup final shocked many experts, and all of a sudden the Brazilians have expectations on them. Whilst you can't argue with that scoreline, we still wonder if Brazil have the firepower to win such a long tournament. Neymar is expected to conjure up the magic, but they're relying on Fred to come up with the goals. No disrepect to Fred, but the last two Brazilian teams to win the World Cup, in 2002 and 1994, could count on the likes of Ronaldo and Romario to lead the front line, two genuine legends of the game.
12月工业利润下滑突显出中国工业面临的产能过剩和价格下跌的困扰,这加大了中国政府放松货币政策并扩大基础设施支出,以缓和经济放缓影响的压力。
“Policymakers around the world are cognisant of the impact the Fed decision will have and are worried, which makes us worried,” said Simon Lue-Fong, head of global emerging debt at Pictet Asset Management. “People are saying the decision is priced in but seeing as no one knows exactly what will happen how can that possibly be true.”
6.微型人脑

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

The report also shows that despite the rising pension insurance balance since 2012, the payable number of months fell to 17.7 months last year from 19.7 months in 2012.
报告称,名校学生的创业意愿较低,或许因为创业机会成本高。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
From the themed collection: 未来已来,新工具赋能城市新时代
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

大多数成功的创业者都遵循类似的模式,并且具备类似的基本特质。无数在线文章和图书宣称掌握了商业成功的秘诀,但事实上其中大多数都可以归结为几个相同的要点。
单词temporary 联想记忆:

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

[di'zain?]

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

The country's improved performance has notched the 17th place in "innovation quality", an indicator that looks at the caliber of universities, number of scientific publications and international patent filings.
借助于Artnet等公布拍卖结果的数据库,如今购买艺术品的富豪非常清楚要想在早期绘画大师的作品上获利非常困难。
Ronaldo and Messi are the only football players in the top 20, which also features no women.
Guangdong has cemented its position as the country's largest provincial economy for the 28th consecutive year, with its gross domestic product (GDP) exceeding 7.9 trillion yuan in 2016.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

n. 疫苗
Gunmen kidnapped 18 Turkish workers Wednesday in Iraq's capital.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
From the themed collection: 国开行棚改项目审批权回收总行
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

7、《海底总动员2》
Have a love filled New Year!
Lisa Stone

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
From the themed collection: 家居以旧换新拉动力为“零”
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

列表里一些电影还在2月份的第67届柏林国际电影节上获得了奖项,例如最佳影片奖得主《身体和灵魂》和最佳导演奖得主《希望的另一面》(芬兰阿基·考里斯马基作品)。
British business schools make up ground on their French counterparts in the revamped Financial Times ranking of masters in management degrees.
纽约州莱维敦的五年级学生张天羽在10万名参赛者中脱颖而出,赢得了本年度谷歌国际少年绘画大赛冠军。这次比赛的主题是“画一个能使世界变得更好的东西”。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

英国《金融时报》金融硕士排行榜评出了50个最优秀的、面向无金融业工作经验或极少金融业工作经验学生的全日制金融项目,以及5个最优秀的、面向有金融业工作经验学生的全日制项目。排名以对商学院以及对2012届毕业生的调查为基础。排名数据从薪资、职位高低和成就等方面衡量了这届学生在毕业后的3年里取得了多大的成功。
6、A股保卫战

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

在西方国家更新、更广泛的国民身份认同里,白人们也有自己的一席之地。但是除非他们接受这一点,“白”的危机仍会持续存在下去。
供给侧结构性改革:去产能、去库存、去杠杆、降成本、补短板
"It's one of the strangest things that's ever happened to me," Beatty said backstage. "Thank God there were two of us up there," Dunaway responded.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

9. 米拉-库尼斯 1100万美元
11月份,财新赞助的中国综合PMI指数读数为50.5。这是自7月份以来,该指数首次超过50这个区分收缩和扩张的荣枯线。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

Despite the huge production, the focus was on the 40 gorgeous models who walked the runway.
Sina's Weibo service, for example, has long offered features that Twitter lacks, notably a commenting function that allows multiple users to add their own thoughts to a user's posts. Tencent's QQ instant messaging service, which has more than 700 million users, offers additional features such as skins to change the look of the client and serves as a portal for the company to advertise other products and services. Sina declined to comment.
6.You Spend Time Looking For Other Jobs

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

McGowan was born into the polygamous Children of God Cult and ran away from home in her teens.

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
From the themed collection: 全国八成“大棚房”问题完成整改
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

《花千骨》
The system for ensuring responsibility is taken for poverty elimination will be effectively enforced, the strictest possible evaluations and assessments of poverty alleviation will be carried out, and stern measures will be taken to address deception, falsification, and the manipulation of numbers in poverty elimination work. We must see that the results of our poverty elimination earn the approval of our people and stand the test of time.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

He also posted a picture of himself looking at a racially diverse group of children.
For now, D'Aloisio isn't touching the money. 'I'm too young to appreciate the value of it,' he insists. 'I don't have a mortgage, I'm 17. To me, a hundred pounds is a lot. Take that as a benchmark.' Though he's not allowed to comment on Summly's sale price, when pressed he allows that he might one day like to deploy his newfound riches as an angel investor. No one around him seems to think there's a danger that the money will ruin him or that he'll be tempted to spend the rest of his life dissipating on a beach. 'He's pretty well grounded. You wouldn't believe how frugal he is,' says Diane. 'He's got a great engine,' says Lou. 'He won't stop at this.'

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

vt. 安慰,使
据中国国家通讯社新华社(Xinhua)周四的报道,李克强于周三在柬埔寨召开的一次地区领导人会议上发表讲话称,2017年中国经济发展好于预期,对外贸易扭转了两年来的下滑局面。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

Horowitz admitted that while doing so he has had to work carefully to preserve 007's characters and attitude as created by the spy novel’s first author Ian Fleming, who died in 1964.
美国退伍军人节也跟世界其他国家纪年第一次世界大战的节日重合,其中包括英国和英联邦国家澳大利亚以及加拿大的纪念日。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

Lawrence’s 2016 earnings dropped 11.5 percent from her 2015 total of $52 million. Forbes will release its list of the world’s highest-paid actors on Thursday. Last year Robert Downey Jr. topped the list with an estimated $80 million.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

adj. 被识别的;经鉴定的;被认同者 v. 鉴定(id
由于经济增长温和、社会快速老龄化,今年的涨幅较2016年的6.5%有所下降。
Which showed month-on-month prices had fallen – albeit marginally – in Beijing, Tianjin, Shanghai, Shenzhen, Xiamen and Zhengzhou during the second half of the month.
plane

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
From the themed collection: 宜华木业拟更名宜华生活科技
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

久而久之,这种民族融合给球队带了不同寻常的和谐。队中的年轻球员,尤其是切尔西的阿扎尔和卢卡库以及曼联的贾努扎伊,成了许多竞争对手羡慕的对象。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

I know this takes time, but it'll ensure you really know your stuff. And that's why you're going to school. Right?
4.A Sex Video
[r?b]

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
From the themed collection: 地产股短线反弹 明年压力不小
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

在屏幕前对女主人公大喊“不要在深夜独自下楼”,不再是徒劳无用的了。在这款互动式惊悚游戏中,玩家可以控制游戏人物的行动。游戏的剧情由电影制片人拉里o法森顿和格拉哈姆o雷兹尼克与游戏开发商Supermassive Games精心打造。故事中,八位好友被困在遥远的山区度假村,还有一名不受限制的精神病人。游戏群星云集,其中包含《神盾局特工》(Agents of S.H.I.E.L.D)的演员布雷特o道顿,美剧《纳什维尔》(Nashville)的演员海顿o潘妮蒂尔和《极品飞车》(Need for Speed)的演员拉米o马雷克。玩家将控制各个角色探索这个恐怖的世界,试图在黎明到来时存活下来。没有人是安全的。在游戏中,每一个决定都会导致不同的结果。游戏剧本长达一千余页,拥有数百个不同结局等待玩家发掘。蝴蝶效应使得游戏不会有相同的剧情,而唯一不变的是,这款游戏十分惊悚。不要独自一人或是在深夜里尝试它。
这些包括纳米汽车在内的轻巧设计小得甚至连肉眼都不可见。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

在你面试应聘者的时候,有些人得分较高,你认为应该他能得到这份工作,但是招聘主管却改掉分数,招那些他喜欢的人。
Haruhiko Kuroday, the Japanese central bank governor said: “I think we can be cautiously optimistic about the global outlook.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
From the themed collection: 国土部:政府将不再垄断居住用地
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

当然,这得取决于苹果是否能设法用更便宜的零部件、更慢的处理器、分辨率更低的屏幕、以及也许是塑料机身来造出一部330美元的iPhone。而用蒂姆?库克上周在高盛公司(Goldman Sachs)一次会议上的话说,它决不能是个“低劣产品”。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

A party of 108 pandas – performers dressed in costumes – descended on London streets today to promote the plight of the cuddly black and white endangered species.
该报道表示:“乐天将伤害中国人民,后果可能是严重的。”该报道发表之后,中国政府对乐天在中国的商业集团开展了多起调查。
第一架无线电操纵的无人驾驶飞机可追溯到1916年。英国发明家阿奇博尔德·洛设计并试飞了第一架无人遥控飞机。它是为了反攻德国齐柏林飞艇而制作的,在第一次世界大战中参与了对地面攻击的战斗。无人机由木和锡制成,它的机翼用的是其他双翼飞机的较低机翼。总的来说,无人机是有些失败的,因为它的引擎噪音干扰了无线操作。1916年,索普威斯飞松公司也尝试制作无人机,他们将无线电设备放置在无人机的尾部,这样引擎就不会干扰到它的信号。但因一次地面上的意外事故,他们的无人机再未起飞:当洛操作无人机飞到高级军官面前时,他原本计划会在1917年再次试飞无人机。但无人机从卡车的后面发射后,飞了一段时间便因引擎故障而坠毁,差点要了在场的军官的命。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
From the themed collection: 新型建材造就室内外温差12℃
Paper

Length-scale dependence of protein hydration-shell density

The other issue with tanking is Philly, Phoenix, and Brooklyn are all bad teams. It's going to be hard to outflank those outfits.
Financial advisors and asset allocators who had been hoping to see some benefit this year from tactical strategies were also not spared the punishment of a capricious market. Of the top three tactical strategies in the country (Mainstay Marketfield, Good Harbor U.S. Tactical Core, F-Squared Premium AlphaSector Index), two had nearly imploded with double-digit losses while the third found itself under SEC investigation for misleading the public about its historical returns. The other giant tactical manager, Schwab’s $9 billion Windhaven Diversified Growth product, looks to end 2014 with a return close to zero. So much for tactics.
'People go crazy and it gets overwhelming.'
“失业”是金融类最热门的搜索项,其次是“华尔街公司”和“产品召回”。

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

当你和他/她打电话打到很晚,他/她挂了电话,你仍然想念他/她,即使电话只挂了2分钟
迷你剧集/电影类最佳女演员:萨拉?保罗森(Sarah Paulson),《美国罪案故事:公诉辛普森》(The People v. O. J. Simpson: American Crime Story)

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

位于芬兰赫尔辛基的开发商Remedy Entertainment通过之前的作品《英雄本色》(Max Payne)和《心灵杀手》(Alan Wake)模糊了好莱坞和游戏之间的界限。如今,这家工作室将次世代的图像技术与紧张气氛和电视剧剧本结合了起来。故事设置在Riverport大学城,玩家将控制杰克o乔伊斯和贝斯o怀尔德。这两人原本是普通人,但在一次导致时间裂缝的意外中,他们获得了操纵时间的超能力。在游戏过程中,时间体系会随时崩溃,导致环境中的时间暂停、断续、倒流和冻结。玩家在游戏中会与帝王联盟(Monarch Corporation)展开对抗,喜欢《英雄本色》中子弹时刻的玩家,可以在放大时间因素的枪战中寻找新的战略。除了虚拟的故事情节,游戏还采用了定制的实景真人叙事模式,根据玩家的不同选择将产生不同的后果。
Finance is one of top school Edhec’s core strengths, both in terms of teaching and research. The school in 2001 established the Edhec-Risk Institute to produce and distribute research on areas such as asset and risk management.
5. Constantly take action.

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
156 items - Showing page 1 of 3

About this collection

认真思考一下:未来的经历能提高你的知识和技能吗?它是否会让你接触到新的观点,认识不同的人?(这些都是支持你对机会说“Yes”的好理由!)你需要为了管理团队或与经验更加丰富的同事共事而培养新技巧吗?如果答案是肯定的,那就接受这种挑战,走出你的舒适区。
然而,在开始攻读EMBA课程之前,男女学员之间已然存在巨大的薪资差距,女性平均薪资较男性低15%,女性和男性的这个数字分别为11.1万美元和12.8万美元。

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